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Pim
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IH01166
SGI-1776
SGI-1776是一种新型的ATP竞争型Pim1和FLT3抑制剂。同时在白血病原代细胞中能够通过降低Mcl-1蛋白的表达而起到细胞毒的作用。
前列腺癌,淋巴瘤
Kim W, et al. Pharmacol Res. 2013 Apr;70(1):90-101.
Chen LS, et al. Blood. 2011 Jul 21;118(3):693-702.
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